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HYPERTENSION

Helen is a 42-year-old overweight female presenting with a resting blood pressure measurement of 190/102. Helen reports swelling feet and ankles, overwhelming fatigue, and “seeing spots”. She has a history of frequent kidney stones, slightly elevated blood sugar, and pet dander allergies.
Helen and her physician agree that a wise place to start treatment is with a blood pressure medicine that combines an angiotensin II receptor blocker with a diuretic.

16. What are the roles of angiotensinogen, angiotensin I, and angiotensin II in the maintenance of blood pressure?

18. How does a diuretic work and how does its action help to lower blood pressure?